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目前,已有关于高抑制细胞活性导致免疫未成熟性的报道.近来又有试验证明,成年鼠的功能性巨噬细胞能增强新生鼠的免疫活性,降低新生期的抑制细胞活性.由此可以认为,新生鼠免疫未成熟性是由于功能性巨噬细胞缺乏和高抑制细胞活性两种因素相互作用的结果.出生后,巨噬细胞的数目和/或功能逐渐增加导致抑制细胞的功能和/或数目逐渐降低,免疫功能随之出现.
At present, there are reports on the high inhibition of cell activity leading to immature immature.Recent experiments have shown that adult mice with functional macrophages can enhance the immunocompetence of neonatal rats, reducing neonatal inhibition of cell activity.Thus can be It is believed that immature immature immunity in immunocompetent newborn mice results from the interaction between a lack of functional macrophages and a high inhibitory activity of the cells.After birth, the gradual increase in the number and / or function of macrophages results in inhibition of the function of the cells and / Or gradually reduce the number of immune function ensued.