论文部分内容阅读
抗凝血酶Ⅲ(ATⅢ)系由肝脏合成,对凝血因子Ⅻ、Ⅺ、Ⅹ均有抑制作用,但主要抑制凝血酶的活性。ATⅢ缺陷常可增加血栓栓塞的发生率,但它对术后病人深部静脉血栓形成(deep venous thrombosis,DVT)的作用未能肯定,尚有争议。作者对57名术前未给抗凝治疗的腹部手术病人,分别于术前、术中及术后8天内测定ATⅢ水平,并于术后第8天作双侧静脉造影。结果发现:①术中ATⅢ水平立即下降,术后第1、2天ATⅢ平均值
Antithrombin Ⅲ (AT Ⅲ) is synthesized by liver and has inhibitory effects on blood coagulation factors Ⅻ, Ⅺ and Ⅹ, but mainly inhibits the activity of thrombin. ATⅢ deficiency can often increase the incidence of thromboembolism, but its role in postoperative deep venous thrombosis (DVT) is not sure, is still controversial. The author of 57 patients without preoperative anticoagulation treatment of abdominal surgery patients were measured before, during and 8 days after the operation AT Ⅲ levels, and in the 8th day after surgery for bilateral venography. The results showed: ① intraoperative AT Ⅲ levels immediately decline, the first and second days after the AT Ⅲ average