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目的：评估９９ｍＴｃ－乙撑双半胱氨酸二乙酯（ＥＣＤ）－ＳＰＥＣＴ脑血流灌注显像对全身发作型癫痫（包括癫痫大发作和失神小发作）病灶定位诊断的临床价值，并分析其影像学特点，还与ＣＴ、ＭＲＩ和ＥＥＧ（脑电图）的诊断结果进行对比分析。方法：分别进行ＥＣＴ、ＭＲＩ、ＣＴ显像和ＥＥＧ检查。结果：ＥＣＴ脑血流灌注显像对本型癫痫病灶的阳性检出率为８４．２％（６４／７６），显著高于ＭＲＩ、ＣＴ和ＥＥＧ。而ＥＥＧ的阳性检出率也达５２．６％（４０／７６），但它的定位诊断价值较小。从ＥＣＴ检出的病灶在脑叶分布特点看：颞叶最多，其次分别为额叶、枕叶和顶叶。结论：ＥＣＴ显像的探测灵敏度显著高于ＭＲＩ、ＣＴ和ＥＥＧ，定位诊断价值也优于ＥＥＧ检查。全身发作型癫痫的脑ＥＣＴ血流灌注影像表现为多个脑叶同时受累或一侧颞叶受累，其构成比例显著高于其它脑叶受累者
OBJECTIVE: To evaluate the clinical value of 99mTc-ethylene bis-cysteine diethyl ester (ECD) -SPECT perfusion imaging in the localization and diagnosis of generalized seizures (including epileptic seizures and absence seizures) Its imaging features, but also with CT, MRI and EEG (EEG) diagnostic results for comparative analysis. Methods: ECT, MRI, CT imaging and EEG were performed respectively. Results: The positive rate of ECT for cerebral infarction was 84.2% (64/76), which was significantly higher than that of MRI, CT and EEG. The positive detection rate of EEG was also 52.6% (40/76), but its diagnostic value of localization was small. Lesions detected from ECT in the distribution characteristics of brain lobes: the largest number of temporal lobe, followed by frontal, occipital and parietal lobes. Conclusion: The detection sensitivity of ECT imaging is significantly higher than that of MRI, CT and EEG, and the diagnostic value of ECT is superior to that of EEG. The brain ECT perfusion imaging in patients with generalized seizure showed multiple cerebral lobe involvement or temporal lobe involvement, the proportion of which was significantly higher than that of other brain lobe involvement