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笔者复习有关文献,将治疗小儿神经性尿频症常用而有效的药物简介如下。1.硝苯啶:系钙通道阻滞剂,能有效地抑制钙离子向细胞内流动,降低平滑肌细胞内钙离子浓度,使逼尿肌松弛,膀胱蓄尿增多。有人用硝苯啶治疗小儿神经性尿频症40例,剂量0.5～1mg/kg·d,分3次口服,3天为1疗程,结果1个疗程治愈28例,2个疗程全部治愈。2.654-2:为乙酰胆碱药,可使支配膀胱的胆碱能神经兴奋性降低,致膀胱逼尿肌松弛,括约肌收缩,从而达到减少排尿次数,增加膀胱尿液蓄积的作
The author review the literature, the treatment of pediatric neurogenic frequent urination and effective drugs are as follows. 1. nifedipine: Department of calcium channel blockers, can effectively inhibit the flow of calcium ions to the cells, reducing the concentration of calcium ions in smooth muscle cells, so that detrusor muscle relaxation, increased urinary bladder. Some people use nifedipine treatment of pediatric neurogenic pollaki 40 cases, the dose of 0.5 ~ 1mg / kg · d, 3 times orally, 3 days for a course of treatment, the results of a course of cure in 28 cases, 2 courses were all cured. 2.654-2: acetylcholine drugs, can control the excitability of the bladder innervation of cholinergic nerve, resulting in detrusor of the bladder relaxation, sphincter contraction, so as to reduce the frequency of urination and increase the accumulation of bladder urine for