重症联合免疫缺陷病的研究进展

• 作 者: 沈国秋 郭履赒
• 机 构: 上海第一医学院儿科医院,上海第一医学院儿科医院
• 出 处: 国外医学(免疫学分册)
• 发表日期: 1985年01期
• 关键词: SCID 印地安人 抗体反应 联合免疫缺陷病 淋巴细胞分化 细胞免疫 异质性 先天性异常 胸腺素 免疫重建

重症联合免疫缺陷病(Severe Cembined immunodeficiency disease,SCID)是代表一组淋巴细胞分化先天性异常的(异质性)综合征.其特征为T和B细胞严重的缺陷,缺乏细胞免疫和抗体反应.此病常在生后3个月开始起病,不治疗大多在2岁内死亡.O’Reilley等研究在加拿大亚大巴卡斯河地的印地安人、阿伯支族印地安人和拿佛和人SCID的发病率

Severe combined immunodeficiency disease (SCID) is a (heterogeneous) syndrome that represents a group of congenital abnormalities in lymphocyte differentiation characterized by severe defects in T and B cells, lack of cellular immunity and antibody responses. The disease often starts in 3 months after birth, most of the treatment is not within 2 years of death.O’Reilley other research in Canada’s Kaspersky Indian, Aboriginal Indians and take Buddha and human SCID incidence