论文部分内容阅读
自1993年1月起,我们将酚妥拉明与前列腺素E_1合用治疗急性乙型肝炎52例,疗效满意,现报告如下。 1 临床资料 六年来,我们肝病专科共收住急性乙型肝炎胆汁郁滞型104例,其中男58人,女46人,年龄26～61岁,平均32岁,104例均为HBsAg、HBeAg和抗HBC阳性,肝功能检查ALT均在78～1618U,胆红素均>160μmol/L,根据其意向分为治疗组和对照组各52人,两组病人在性别、年龄、肝炎病程及肝功能检查情况等方面均无明显统计学差异(P>0.05)。 2 治疗方法 治疗组用酚妥拉明20mg加入10％葡萄糖500ml内,静脉滴注,每分钟20～25滴,每天1次,用至血清胆红素恢复正常后停药,同时用前列腺素E_1,每次300mg加入5％葡萄糖250ml中静脉滴注,每天1次,连用30天为一疗程。对照组用猪苓多糖、肝泰乐及肌苷肌注。口服香菇菌多糖片,甘草甜素片等。治疗每隔2周查肝功能1次,每隔1个月查1次两对半。 3 疗效 显效:临床症状、体征消失,肝功能检查血清ALT及胆
Since January 1993, we have combined phentolamine and prostaglandin E_1 in the treatment of 52 cases of acute hepatitis B, with satisfactory results, are as follows. Clinical data Six years, our liver specialist admitted a total of 104 cases of acute hepatitis B cholestasis type, including 58 males and 46 females, aged 26 to 61 years, mean 32 years, 104 cases were HBsAg, HBeAg and Anti-HBC positive, liver function tests ALT were 78 ~ 1618U, bilirubin were> 160μmol / L, according to their intention to be divided into treatment group and control group of 52 people, two groups of patients in gender, age, duration of hepatitis and liver function Examination, etc. There was no statistically significant difference (P> 0.05). 2 treatment of treatment group with phentolamine 20mg added 10% glucose 500ml, intravenous infusion of 20 to 25 drops per minute, once daily until the serum bilirubin returned to normal after withdrawal, at the same time with prostaglandin E_1 , 300mg each time by adding 5% glucose 250ml intravenous infusion, once daily, once every 30 days for a course of treatment. The control group with Polyporus umbellatus, heptahydrate and inosine intramuscular injection. Oral mushroom mushroom polysaccharide tablets, licorice tablets and so on. Treatment of liver function check every 2 weeks 1, every 1 months check 1 two and a half. 3 effect markedly: clinical symptoms, signs disappeared, liver function test serum ALT and gallbladder