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回顾性分析本院1988-1998年收治的22例原发性胃非何杰金氏淋巴瘤患者的临床资料。胃窦部12例,胃体7例,胃小弯1例,胃大弯2例。根治性切除17例,姑息性切除4例,化疗1例,术后予CHOP、COAP方案化疗5-8疗程,随访10年。1年存活率14/21,3年存活率9/16,5年存活率6/12。结果表明,对原发性胃非何杰金氏淋巴瘤的特征性溃疡应常规作免疫组化,能提高术前确诊率及减少误诊率。根治性手术切除及术后足够疗程、足够强度化疗能提高存活率。
We retrospectively analyzed the clinical data of 22 patients with primary gastric non-Hodgkin’s lymphoma admitted to our hospital from 1988 to 1998. There were 12 cases of gastric antrum, 7 cases of gastric body, 1 case of small curvature of stomach, and 2 cases of large curvature of stomach. Radical resection in 17 cases, palliative resection in 4 cases, chemotherapy in 1 case, postoperative CHOP, COAP chemotherapy 5-8 courses of treatment, followed up for 10 years. The 1-year survival rate was 14/21, the 3-year survival rate was 9/16, and the 5-year survival rate was 6/12. The results showed that the characteristic ulcers of primary gastric non-Hodgkin’s lymphoma should be routinely immunohistochemically, which can increase the preoperative diagnosis rate and reduce the rate of misdiagnosis. Radical surgical resection and adequate course of treatment, adequate intensity chemotherapy can improve survival.