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目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与冠心病相关因素的关系。方法:利用冠状动脉造影及便携式睡眠监测系统对127例胸痛或胸闷的鼾症患者进行分组,并对其血糖、胆固醇、尿酸、高敏C反应蛋白及纤维蛋白原进行分析,比较其相关性。结果:OSAHS组与对照组间年龄、甘油三脂、胆固醇无统计学差异,血糖、尿酸、高敏C反应蛋白及纤维蛋白原差异有统计学意义。OSAHS组合并冠心病,肥胖及高脂血症的百分率与对照组比较有统计学意义。结论:在冠心病的发病过程中,OSAHS的参与及严重程度和冠心病发病密切相关。
Objective: To investigate the relationship between obstructive sleep apnea hypopnea syndrome (OSAHS) and coronary heart disease related factors. Methods: 127 cases of snoring patients with chest pain or chest tightness were grouped by coronary angiography and portable sleep monitoring system. The levels of blood sugar, cholesterol, uric acid, high-sensitivity C-reactive protein and fibrinogen were analyzed and their correlations were compared. Results: There was no significant difference in age, triglyceride and cholesterol between OSAHS group and control group. There was significant difference in blood glucose, uric acid, high-sensitivity C-reactive protein and fibrinogen between OSAHS group and control group. OSAHS combined with coronary heart disease, obesity and hyperlipidemia percentage compared with the control group was statistically significant. Conclusion: In the pathogenesis of coronary heart disease, the involvement and severity of OSAHS are closely related to the incidence of coronary heart disease.