The point mutation of p53 gene exon7 hepatocellular carcinoma from Anhui Province,anon HCC prevalent

• 作 者: LiuH WangY 等
• 机 构: LaboratoryofMolecularBiologyandDepartmentofBIochemistry,LaboratoryofMolecularBiologyandDepartmentofB
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2002年3期
• 关键词: 肝癌细胞 非肝细胞癌流行区 基因突变 Genes p53Base SequenceCarcinoma HepatocellularChinaDNA Neo
• 基金项目: the Natural Science Foundation of Anhui Province,No.99044312(WY) and No.9741006(LX),,Natural Science Foundation of Anhui Educational Commission,No.JL-97-077(WY).

AIM：In hepatocellular carcinoma(HCC)prevalent areas of China,the point mutation of p53 exon7 is highly correlated with hepatitis B virus(HBV)infection and aflatoxin B intake While in non-HCC_prevalent areas of China,these factors are not so important in t