论文部分内容阅读
高胆固醇血症病人和胆固醇饲养动物的血浆中胆固醇酯转移蛋白（CETP）的浓度和活性均升高。胆固醇酯转移（CET）水平的高低取决于CETP及脂蛋白的数量和质量。胆固醇酯向合apoB的脂蛋白的转移可产生易于氧化的LDL亚类。已经发现，改变脂质成分的饮食和药物可降低血浆中CETP的活
Plasma cholesterol cholesteryl ester transfer protein (CETP) concentrations and activities were elevated in hypercholesterolemic and cholesterol-fed animals. The level of cholesterol ester transfer (CET) depends on the quantity and quality of CETP and lipoprotein. Transfer of cholesteryl esters to lipoproteins associated with apoB can generate LDL subclasses that are readily oxidized. It has been found that diet and drugs that alter lipid composition can reduce CETP activity in plasma