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1976年我们曾观察甲氧苄氨嘧啶(TMP)加半量磺胺嘧啶(SD)治疗流脑的疗效(发表在本刊1976年第五期)。1977年2～4月,我们又选择120例普通型流脑,再次观察TMP加半量SD治疗流脑的疗效,并与单用SD及氯霉素治疗作比较,显示TMP+SD组较SD组为优,现总结如下: 用药方法:SD组,儿童剂量为150～200毫克/公斤/日,静滴为100～150毫克/公斤/日,成人为6克/日;TMP+SD组,TMP的儿童剂量为5～10毫克/公斤/日,成人为0.4克/日,SD剂量为前组的半量;氯霉素组,儿童剂量为50毫克/公斤/日,成人为2.0～2.5毫克/日,
In 1976, we observed the efficacy of trimethoprim (TMP) plus half the dose of sulfadiazine (SD) in the treatment of meningitis (published in Issue 5, 1976). From February to April 1977, we selected 120 cases of common meningitis again to observe the efficacy of TMP plus half of SD in the treatment of meningitis. Compared with SD and chloramphenicol alone, As the best, are summarized as follows: Drugs: SD group, children dose of 150 to 200 mg / kg / day, intravenous infusion of 100 to 150 mg / kg / day, adult 6 g / day; TMP + SD group, TMP Of children had a dose of 5 to 10 mg / kg / day, an adult of 0.4 g / day, an SD dose of half the amount of the former group, a chloramphenicol group of 50 mg / kg / day for children and 2.0 to 2.5 mg / day,