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目的 通过对 85 0例糖筛查异常孕妇口服 75 g葡萄糖耐量试验 (OGTT)结果和妊娠结局的分析 ,了解妊娠期糖代谢异常不同诊断标准与妊娠结局的关系。 方法 对 2 0 0 1年 1月 1日至 2 0 0 3年12月 3 1日在我院分娩、5 0 g糖筛查异常、OGTT结果不符合我院使用的Fernando标准、未诊断妊娠期糖尿病 (GDM )和糖耐量受损 (GIGT)的 85 0例孕妇进行回顾性研究。将 85 0例孕妇分成两组 :符合董志光等人妊娠期糖尿病 (GDM )和糖耐量受损标准组 (第一组 )及不符合组 (第二组 )。 结果 妊娠期糖代谢异常发生率为 2 3 .76% (2 0 2例 ) ,以董志光诊断标准 ,其中GDM 3 7例 ,占 4.3 5 % ,IGT 165例 ,占 19.41%。新生儿平均出生体重为 (3 461.4± 475 .9)g ,高于不符合组 [(3 40 7.8± 43 8.4) g ,P <0 .0 1]。巨大儿发生率虽高一些 ,但无统计学差异。剖宫产率两组间也无差异。妊娠期合并症如妊娠高血压综合征、胎膜早破和早产的发生率 ,以及新生儿低血糖、黄疸和低出生体重儿的发生率两组间均无差异。 结论 按Fernando标准 ,糖筛查异常人群中将有 2 3 .76%的糖代谢异常者被漏诊 ,但发生妊娠高血压综合征、胎膜早破、早产、剖宫产、新生儿低血糖、黄疸和低出生体重儿的危险性并无明显增加。如按董志光等人的标准 ,将?
OBJECTIVE: To understand the relationship between different diagnostic criteria of gestational glucose metabolism abnormalities and pregnancy outcomes by analyzing oral glucose tolerance test (OGTT) results and pregnancy outcome of 85 0 pregnant women with abnormal glucose screening. Methods From January 1, 2001 to December 31, 2003 in our hospital for delivery, 50 g of sugar screening abnormalities, OGTT results do not meet the Fernando standard used in our hospital, not diagnosed during pregnancy A retrospective study was conducted on 85 0 pregnant women with diabetes mellitus (GDM) and impaired glucose tolerance (GIGT). 850 pregnant women were divided into two groups: in line with Dong Zhiguang et al gestational diabetes (GDM) and impaired glucose tolerance standard group (first group) and non-compliance group (second group). Results The incidence of abnormal glucose metabolism in gestation was 23.76% (202 cases). According to the diagnostic criteria of Dong Zhiguang, there were 7 cases of GDM (4.3%) and 165 cases of IGT (19.41%). The average newborn birth weight was (3 461.4 ± 475.9) g, which was higher than that of the non-compliance group [(3 40 7.8 ± 43 8.4) g, P <0.01]. The incidence of macrosomia was higher, but no statistical difference. There was no difference between the two groups in cesarean section rates. Pregnancy complications such as pregnancy-induced hypertension, the incidence of premature rupture of membranes and premature birth, as well as neonatal hypoglycemia, jaundice and low birth weight children were no difference between the two groups. Conclusion According to the Fernando standard, 23.76% of patients with abnormal glucose metabolism will be missed by the sugar screening abnormality group. However, pregnancy-induced hypertension syndrome, premature rupture of membranes, premature labor, cesarean section, neonatal hypoglycemia, There was no significant increase in the risk of jaundice and low birth weight infants. According to Dong Zhiguang et al. Standards, will?