论文部分内容阅读
本实验旨在通过对非心源性胸痛和有烧心症状患者的观察,阐明胃食管返流疾病中症状性胃食管返流、食管粘膜酸敏感性及食管异常酸浸渍三者之间的相互关系。受试患者50例,其中9例非心源性胸痛,41例可疑胃食管返流(有烧心病史)。采用(1)酸灌注试验:检查食管对酸的敏感性。通过导管在距食管下括约肌7cm处向食管注入NS,速度为6ml/min,共7min;如无症状出现,提高到14ml/min,共8min。然后注入0.1N HCI,6ml/min,共7min;如无症状引出,增加到14ml/min,共8min。在注入HCI时患者出现胸痛,不适或烧心为阳性。(2)23小时pH监测:检查患者食管的酸浸渍时间及症状性食管返流。采用内装参
This experiment aims to clarify the relationship between symptomatic gastroesophageal reflux, esophageal mucosal acid sensitivity and esophageal anomalous acid soaking in gastroesophageal reflux disease through observation of non-cardiac chest pain and patients with heartburn symptoms . Fifty patients were tested, including 9 non-cardiac chest pain and 41 suspicious gastroesophageal reflux (with a history of heartburn). Using (1) acid perfusion test: check the sensitivity of the esophagus on the acid. Into the esophagus by catheter at a distance of 7cm from the lower esophageal sphincter NS, the speed of 6ml / min, a total of 7min; if no symptoms, increased to 14ml / min, a total of 8min. Then inject 0.1N HCI, 6ml / min, a total of 7min; asymptomatic leads, increased to 14ml / min, a total of 8min. Chest pain, discomfort, or heartburn were positive in HCI-infused patients. (2) 23 hours pH monitoring: Check the patient’s esophagus acid immersion time and symptomatic esophageal reflux. With built-in reference