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肝脑综合征病情复杂,转化迅速,病死率高。本文分析143例肝脑综合征的诱因及预后相关因素。本组中男性105例,女性38例。原发病肝硬化63例,急性重症肝炎56例,慢性重症肝炎17例,原发性肝癌6例,中毒性肝炎1例。年龄2月~68岁。诱因:低血钾62例次(43.4%),原发性腹膜炎45例次(31.5%),消化道出血35例次(24.5%),胆道感染22例次(15.4%),其它与肺部、肠道及尿路感染,利尿剂,手术,分娩,过度劳累,饮酒及药物有关。急性重症肝炎多数无诱因,肝硬化病人均有诱因存在。凝血酶原时间越长病情越重,如经治疗其时间迅速缩短提示预后良好。甲胎蛋白一过性升高提示肝细胞再生力强,预后与昏迷次数及持续时间无明显相关性,与昏迷程度呈
Liver syndrome is complicated, rapid transformation, high mortality. This article analyzes 143 cases of liver and brain syndrome causes and prognosis related factors. This group of 105 males and 38 females. Primary cirrhosis in 63 cases, acute severe hepatitis in 56 cases, 17 cases of chronic severe hepatitis, 6 cases of primary liver cancer, 1 case of toxic hepatitis. Age from February to 68 years old. Incentives: hypokalemia in 62 cases (43.4%), 45 cases of primary peritonitis (31.5%), gastrointestinal bleeding in 35 cases (24.5%), biliary tract infection in 22 cases (15.4%), the other with the lung , Intestinal and urinary tract infections, diuretics, surgery, childbirth, overwork, alcohol and drugs. Most of the patients with acute severe hepatitis have no incentive, and there are incentives for patients with liver cirrhosis. The longer the prothrombin time the more serious the condition, if its time is shortened promptly, the prognosis is good. A transient increase in alpha-fetoprotein suggests a strong regenerative capacity of hepatocytes, with no correlation between prognosis and coma frequency and duration,