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调查了苏丹中部曼氏血吸虫病重度流行区58例晚期肝脾型血吸虫病病人血清蛋白浓度和酶活性,并与40例健康供血者进行了对照。58例病人(男性51例,女性7例,年龄为15～60岁,平均35岁)均曾有粪中排卵史和至少一次由门脉高压引起的呕血和/或黑便史。诊断标准如下:16例病人经肝组织活检诊断为血吸虫病性门脉周围纤维化,18例病人用超声扫描器诊断为门脉周围纤维
Serum protein concentrations and enzyme activities were measured in 58 patients with advanced hepatomegaly and schistosomiasis in the endemic area of Schistosoma mansoni in central Sudan and compared with 40 healthy donors. Fifty-eight patients (51 males, 7 females, aged 15-60 years, mean 35 years) had history of ovulation in feces and at least one history of vomiting and / or melena caused by portal hypertension. Diagnostic criteria are as follows: Sixteen patients were diagnosed as schistosomal fibrosis around the portal by biopsy of the liver, and 18 were diagnosed as fibrovascular around the portal by ultrasound scanners