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目的 评价小儿热感宁口服液 (XRK)治疗小儿上呼吸道感染 (上感 )的疗效及安全性。方法 12 0例上感患儿随机分成观察组 (6 0例 )和对照组 (6 0例 ) ,观察组口服 XRK的剂量为 :1岁以内 2 .5～ 5 ml,1～ 3岁 5～ 10 ml,3～ 7岁 10～ 15 m l,7～ 13岁 15～ 2 0 ml,1日 3～ 4次 ,首剂加倍 ,3日 1疗程。记录患儿用药前后的体温、临床症状及不良反应 ,并按标准作出疗效评定 ,对照组口服维 C银翘冲剂治疗 ,并对两组进行疗效比较。结果 观察组显效 44例 (73.3% ) ,好转8例 (13.3% ) ,无效 8例 (13.3% ) ,总有效率为 86 .6 % ,未发现与本药治疗有关的不良反应。对照组显效 2 6例 (4 3.3% ) ,好转 18例 (30 % ) ,无效 16例 (2 6 .7% ) ,总有效率为 73.3%。两组显效率比较 P <0 .0 1。结论 小儿热感宁口服液是一种临床治疗小儿上感的安全有效的中西药复方制剂
Objective To evaluate the efficacy and safety of pediatric heat sensitive oral liquid (XRK) in the treatment of pediatric upper respiratory tract infections (upper flu). Methods A total of 120 children were randomly divided into observation group (60 cases) and control group (60 cases). The dosage of oral XRK in observation group was 2.5-5 ml within 1 year, 10 ml, 3 ~ 7 years old 10 ~ 15 ml, 7 ~ 13 years old 15 ~ 20 ml, 1 day 3 to 4 times, the first dose doubled, on the 3rd of a course of treatment. The body temperature, clinical symptoms and adverse reactions of children before and after treatment were recorded, and the curative effect was evaluated according to the standard. The control group was treated with Vitamin C Yinqiao Granule, and the curative effect was compared between the two groups. Results The observation group was significantly improved in 44 cases (73.3%), improved in 8 cases (13.3%), ineffective in 8 cases (13.3%), the total effective rate was 86.6%. No adverse reactions were found. The control group was effective in 26 cases (4.3%), improvement in 18 cases (30%), ineffective in 16 cases (26.7%), the total effective rate was 73.3%. Significant efficiency between the two groups P <0. Conclusion Pediatric Relieving Oral Liquid is a safe and effective compound preparation of Chinese and Western medicine for clinical treatment of pediatric upper respiratory tract infection