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目的观察缩宫素联合米索前列醇预防产后出血的临床疗效。方法选择2011年5月至2013年5月通许县人民医院80例自然分娩产妇,根据随机数字法,将其分为对照组(缩宫素治疗)和观察组(缩宫素联合米索前列醇治疗),每组40例,比较两组产程进展及产后出血情况,以及治疗前后血压、脉搏变化情况。结果与对照组相比,观察组第三产程明显缩短,产后30 min和2 h出血量明显减少,差异有统计学意义(P<0.05),而治疗前后血压、脉搏比较差异无统计学意义(P>0.05)。结论缩宫素联合米索前列醇能有效预防产后出血,明显减少产后出血量。
Objective To observe the clinical efficacy of oxytocin combined with misoprostol in preventing postpartum hemorrhage. Methods From May 2011 to May 2013, 80 cases of natural childbirth in Tongxu People’s Hospital were divided into control group (oxytocin treatment) and observation group (oxytocin combined with misoprostol Treatment), 40 cases in each group. The progress of labor and postpartum hemorrhage were compared between the two groups. The changes of blood pressure and pulse before and after treatment were also compared. Results Compared with the control group, the third trimester of observation group was significantly shortened, and the amount of hemorrhage was significantly reduced at 30 and 2 h after delivery (P <0.05). There was no significant difference in blood pressure and pulse between before and after treatment (P < P> 0.05). Conclusion Oxytocin combined with misoprostol can effectively prevent postpartum hemorrhage and significantly reduce the amount of postpartum hemorrhage.