Depletion of Kindlin-2 induces cardiac dysfunction in mice

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：a2854831

【摘要】

：

Kindlin-2, a member of the Kindlin family focal adhesion proteins, plays an important role in cardiac development. It is known that defects in the Z-disc protei

【作者】

：

Lihua Qi Yu Yu Xiaochun Chi Da

【机构】

：

DepartmentofHumanAnatomy,InstituteofVascularMedicine

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2016年11期

【基金项目】

：

supported by the Ministry of Science and Technology of China(2015CB553906,2013CB910501),the National Natural Science Foundation of China(81500180,81230051,81472734,31170711,81321003,30830048),Beijing

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Kindlin-2, a member of the Kindlin family focal adhesion proteins, plays an important role in cardiac development. It is known that defects in the Z-disc proteins lead to hypertrophic cardiomyopathy(HCM) or dilated cardiomyopathy(DCM). Our previous invest

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Depletion of Kindlin-2 induces cardiac dysfunction in mice

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