Hypoxia inducible factor（HIF） in the tumor microenvironment：friend or foe？

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：jay12

【摘要】

：

Hypoxia acts as an important regulator of physiological and pathological processes. Hypoxia inducible factors(HIFs) are the central players involved in the cell

【作者】

：

Yanqing Huang Daniel Lin Culle

【机构】

：

TheUniversityofTexasatMDAnderson,TheUniversityofTexasatMDAnderson

【出处】

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中国科学：生命科学英文版

【发表日期】

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2017年10期

【基金项目】

：

supported by funding from Cancer Prevention ＆ Research Institute of Texas （CPRIT, RR140012）,V Foundation （V2015-2022）,Sabin Family Foundation Fellowship at MD Anderson （2016-00052285）,generous support

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Hypoxia acts as an important regulator of physiological and pathological processes. Hypoxia inducible factors(HIFs) are the central players involved in the cellular adaptation to hypoxia and are regulated by oxygen sensing EGLN prolyl hydroxylases.Hypoxia

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Hypoxia inducible factor（HIF） in the tumor microenvironment：friend or foe？

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