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目的：观察米托蒽醌及中西医结合治疗急性白血病的临床疗效。方法：将６０ 例急性白血病患者随机分为两组，对照组２７例，采用米托蒽醌为主的联合化疗；治疗组３３例，在用米托蒽醌为主联合化疗的基础上，加用健脾和胃，清热解毒中药。结果：治疗组获完全缓解（ＣＲ）２１例，部分缓解（ＰＲ）１０例，总有效率９３．９４％，明显优于对照组７０．３７％（Ｐ＜０．０５），且临床未见明显毒副反应。结论：米托蒽醌为主联合方案治疗急性白血病疗效良好，毒副反应较轻，合用健牌和胃、清热解毒中药，可提高疗效，减轻毒副反应。
Objective: To observe the clinical efficacy of mitoxantrone and combination of traditional Chinese and western medicine in the treatment of acute leukemia. Methods: Sixty patients with acute leukemia were randomly divided into two groups, the control group, 27 cases, the use of mitoxantrone-based combination chemotherapy; treatment group, 33 cases, with mitoxantrone-based combination chemotherapy, plus Spleen and stomach, detoxification traditional Chinese medicine. Results: In the treatment group, 21 patients were completely relieved (CR), 10 patients achieved partial response (PR), the total effective rate was 93.94%, which was significantly better than that of the control group (70.37%, P <0.05) Significant toxic side effects. Conclusion: Mitoxantrone is the main combination regimen for the treatment of acute leukemia with good curative effect and mild side effects. Combination of Chinese herbs and stomach, detoxification and traditional Chinese medicine can improve curative effect and reduce side effects.