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成都塑料厂医务室:本症是一个粒细胞缺乏的综合病症。早在1902-1907年即有记载。指明病程急进,发生感染,极度衰蝎,血中粒细胞高度减少甚至消失。经过70年的实践,认识到它是一个由多种原因引起的综合病症。一、一般病因与常见的致病因素:本病一般的病因有:1.慢性婴儿中性粒细胞减少症;2.药物所致的中性粒细胞减少症;3.免疫病粒细胞减少症;4.胰腺与骨髓功能不全;5.小儿慢性良性粒细胞减少症;6.再生障碍贫血与白血病,7.无效髓生成;8.免疫性粒细胞减少症;9.脾原性粒细胞减少;10.肝病性粒细胞减少;11.家族性粒细胞减少症;12.周期性粒细胞减少症;13.放射线病。其中最常见的是药物所致的粒细胞减少症,近十几年来引起本症的药物已有报道的有:1.抗菌素类:青霉素、链霉素、四环素族(地、金、合、氯、四),新青霉素Ⅰ,磺胺类(磺胺脒、长效磺胺、氨苯磺胺、磺胺吡啶、磺胺噻唑、乙酰唑胺)、黄连素等。 2.解热剂:醋柳酸、安替匹林、扑热息痛、索米通、氨基匹林、辛可芬、去痛片、安乃近,银翘解毒丸、羚翘解毒丸(后两药
Chengdu Plastic Factory Medical Office: The disease is a combination of agranulocytosis. As early as 1902-1907 that there are records. Indicate the course of the disease, the occurrence of infection, extreme bad scorpion, blood, reduce or even reduce the height of granulocytes. After 70 years of practice, I realized that it is a complex condition caused by many reasons. First, the general etiology and common risk factors: The general causes of the disease are: 1. Chronic infantile neutropenia; 2. Drug-induced neutropenia; 3. Immunotherapy neutropenia ; 4. pancreas and bone marrow dysfunction; 5. children with chronic benign neutropenia; 6. aplastic anemia and leukemia, 7. invalid marrow; 8. immune cytokinesia; 9. splenic neutropenia ; 10. Hepatic neutropenia; 11. Familial neutropenia; 12. Cystic neutropenia; 13. Radiation disease. One of the most common is the drug-induced neutrophils, drugs that have caused this disease in the past decade or so have been reported: 1. Antibiotics: penicillin, streptomycin, tetracyclines (gold, , Four), new penicillin Ⅰ, sulfonamides (sulfanilamide, long-acting sulfonamide, sulfamethoxazole, sulfapyridine, sulfathiazole, acetazolamide), berberine and so on. 2. Antipyretics: Acetisine, Antipyretics, Paracetamol, Somitong, Amino-Pirin, Xin Kefen, to pain tablets, analgin, Yinqiao detoxification pills, Lingxuejiedu pills (the latter two drugs