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目的研究分析医院感染鲍曼不动杆菌的临床分布特点及耐药性。方法选择2013年12月-2014年4月医院住院部收集的鲍曼不动杆菌135株进行研究,分离培养后应用全自动微生物分析仪鉴定,并使用药敏卡展开药敏试验。结果 135株鲍曼不动杆菌中89株从痰液标本中获取占65.9%,咽拭子、分泌物和尿液分布占10.4%、5.9%、4.4%;鲍曼不动杆菌的科室分布中ICU占的比例最高,为31.1%,其余依次是呼吸内科(18.5%)、普外科(15.6%)、神经外科(11.1%)等;鲍曼不动杆菌对磺胺甲噁唑/甲氧苄啶、头孢替坦、头孢呋辛酯、头孢呋辛、头孢唑林等药物的耐药性十分高,对替卡西林/克拉维酸、阿米卡星、头孢哌酮/舒巴坦等药物的耐药性相对较低。结论医院感染中鲍曼不动杆菌十分常见,在ICU病房中最常见,且对鲍曼不动杆菌的耐药性较高,临床上需要采取有效的措施,合理用药。
Objective To study the clinical distribution and drug resistance of Acinetobacter baumannii in hospital. Methods 135 strains of Acinetobacter baumannii collected in hospital inpatients from December 2013 to April 2014 were selected for study. After isolation and culture, the samples were identified by automatic microbiological analyzer and susceptibility testing was conducted using drug susceptibility card. Results Among the 135 Acinetobacter baumannii isolates, 89 were obtained from sputum specimens accounting for 65.9%, throat swabs, secretions and urine distribution accounted for 10.4%, 5.9% and 4.4%, respectively. Acinetobacter baumannii ICU accounted for the highest proportion of 31.1%, followed by respiratory medicine (18.5%), general surgery (15.6%), neurosurgery (11.1%); Acinetobacter baumannii sulfamethoxazole / trimethoprim , Cefotetan, cefuroxime axetil, cefuroxime, cefazolin and other drugs is very high resistance to ticarcillin / clavulanic acid, amikacin, cefoperazone / sulbactam and other drugs Drug resistance is relatively low. Conclusion Acinetobacter baumannii is very common in nosocomial infection and most commonly seen in ICU wards, and its resistance to Acinetobacter baumannii is high. Clinically, it is necessary to take effective measures and to use it rationally.