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高效液相色谱法在食品分析中可有效检查出食品的营养成分、食品添加剂的状况以及食品中是否含有有毒物质或非法化学物质。本文简要介绍了高效液相色谱分析和分析的基本原理，并主要介绍了高效液相色谱在食品安全检测中的应用， 表明液相色谱仪的操作方法在食品安全检测中具有重要作用。“,”High performance liquid chromatography can effectively check the nutritional content of food, the status of food additives and whether the food contains toxic or illegal chemical substances in food analysis. This article briefly introduces the basic principles of high performance liquid chromatography analysis and analysis, and mainly introduces the application of high performance liquid chromatography in food safety inspection, indicating that the operation method of liquid chromatograph plays an important role in food safety inspection.