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The article begins with a brief description of the preparation of monoclonal antibodies against uterine cervical cancer, turning then to the long-term culture of relevant hybridoma cells and transfectant cells in serum-free media. In this article, a hypothesis of “evolutionary antigen” is advanced as supported by the presence of a common antigen of human and mouse uterine cervical cancer. In addition, application of the monoclonal antibodies to clinical diagnosis is suggested while the use of these antibodies in the treatment of experimental cancer would seem feasible.
The article begins with a brief description of the preparation of monoclonal antibodies against uterine cervical cancer, turning then to the long-term culture of relevant hybridoma cells and transfectant cells in serum-free media. In this article, a hypothesis of “evolutionary antigen ”is advanced as supported by the presence of a common antigen of human and mouse uterine cervical cancer. In addition while the use of these antibodies in the treatment of experimental cancer would seem feasible.