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柯兴氏综合症高血压柯兴氏综合症是一个以肾上腺皮质功能亢进或肾上腺皮质醇分泌过多为主要病变的临床症候群,包括:向心性肥胖,圆月脸、驼峰背,皮肤菲薄有紫裂纹,四肢肌肉萎缩,软弱无力,骨质疏松,高血压和糖尿病等。病理解剖学基础多样化,主要为双侧肾上腺皮质增生(继发于垂体嗜碱性细胞腺瘤),肾上腺皮质腺瘤或癌瘤、异位肾上腺皮质肿瘤(卵巢门区)、非内分泌组织ACTH分泌肿瘤(支气管肺癌,胸腺瘤等)以及药源性柯兴氏综合症。病理生理变化主要是
Cushing’s Syndrome Hypertension Cushing’s syndrome is a clinical syndrome characterized by hyperadrenalism or hypercortisol secretion, which includes: central obesity, full moon face, humpback, and thin purple skin. Cracks, muscle atrophy of the limbs, weakness, osteoporosis, hypertension and diabetes. The anatomy of pathology is diversified, mainly bilateral adrenocortical hyperplasia (secondary to pituitary basophil adenoma), adrenocortical adenoma or carcinoma, ectopic adrenal cortical tumor (ovarian portal area), non-endocrine tissue ACTH Secretion of tumors (bronchial lung cancer, thymoma, etc.) and drug-induced Cushing’s syndrome. Pathophysiological changes are mainly