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目的:分析丹参制剂不良反应因素。方法:对本院2012年8月至2014年7月125例应用丹参制剂引起不良反应的病例进行回顾性分析,探讨引起不良反应的因素。结果:125例应用丹参制剂引起的不良反应中注射剂型102例,占81.60%;口服制剂23例,占18.40%。患者性别为女性78例,占62.40%;男性47例,占37.60%。患者年龄在60岁以下者20例,占16.00%;60岁~70岁32例,占25.60%;70岁以上者73例,占58.40%。结论:丹参制剂引起的不良反应与剂型、性别、年龄等因素均有关,以注射剂型较多见,女性略多于男性,70岁以上的高龄患者较常见。
Objective: To analyze the adverse reactions of Salvia miltiorrhiza preparations. Methods: A retrospective analysis of 125 patients with adverse reactions caused by Danshen preparation from August 2012 to July 2014 in this hospital was conducted to investigate the factors causing adverse reactions. RESULTS: Of the 125 adverse reactions caused by the use of Salvia miltiorrhiza preparations, 102 were injections, accounting for 81.60%; 23 were oral preparations, accounting for 18.40%. The patient’s gender was 78 females, accounting for 62.40%; 47 males accounted for 37.60%. Patients under the age of 60 were 20 cases, accounting for 16.00%; 60-70 years were 32 cases, accounting for 25.60%; 73 years of age were 73 cases, accounting for 58.40%. Conclusion: Adverse reactions caused by Salvia miltiorrhiza preparations are related to the dosage form, sex, age and other factors. Injections are more common than women, slightly more than men, and older patients over 70 years old are more common.