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目的探讨老年人难控性高血压的治疗方法,进一步了解高血压联合用药的必要性。方法选取185例老年难控性高血压患者,随机分为观察组与对照组,观察组(110例)应用卡维地洛配伍螺内酯治疗,对照组(75例)在原有治疗基础上加用螺内酯治疗,比较二种治疗方法对老年难控性高血压的疗效。结果观察组对难控性高血压患者治疗的有效率明显高于对照组;观察组患者的副作用发生率明显低于对照组;观察组患者左室舒张末期内径和左室收缩末期内径的变化均明显大于对照组。结论卡维地洛联合螺内酯治疗老年难控性高血压效果理想,适合在临床中推广应用。
Objective To explore the treatment of refractory hypertension in the elderly and further understand the necessity of combination therapy of hypertension. Methods 185 cases of elderly patients with refractory hypertension were randomly divided into observation group and control group. The observation group (110 cases) was treated with carvedilol and spironolactone. The control group (75 cases) was treated with spironolactone Treatment, Comparison of two kinds of treatment of elderly refractory hypertension. Results The observation group was significantly more effective than the control group in the treatment of patients with refractory hypertension. The incidence of side effects in the observation group was significantly lower than that in the control group. The change of the left ventricular end-diastolic diameter and left ventricular end-systolic diameter Obviously larger than the control group. Conclusion Carvedilol combined with spironolactone treatment of elderly patients with refractory hypertension ideal effect, suitable for clinical application.