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将38例口服降糖药控制差的T2DM患者(HbA1c>7.5%)随机分为胰岛素泵组(治疗组)20例和胰岛素皮下注射组(对照组)18例,治疗至空腹血糖(FPG)、睡前血糖在目标范围后行动态血糖监测系统(CGMS)监测,分析两组血糖波动性。两组患者的平均血糖、FPG、睡前血糖无显著性差异(P>0.05),但两组最高血糖、最低血糖、血糖的标准差、低血糖发生率均有显著性差异(P<0.05)。结论胰岛素泵治疗较胰岛素皮下注射治疗T2DM,血糖控制更理想,血糖波动性更小。
Twenty-eight T2DM patients with poor control of oral hypoglycemic agents (HbA1c> 7.5%) were randomly divided into insulin pump group (treatment group) and insulin subcutaneous injection group (18 cases), and were given fasting blood glucose (FPG) Before going to bed blood glucose in the target range of dynamic glucose monitoring system (CGMS) monitoring, analysis of two groups of blood glucose fluctuations. There was no significant difference between the two groups in the average blood glucose, FPG, blood glucose before going to sleep (P> 0.05), but there was a significant difference between the two groups in the maximum blood glucose, the lowest blood glucose, the standard deviation of blood glucose and the incidence of hypoglycemia (P <0.05) . Conclusion Insulin pump treatment than insulin subcutaneous injection of T2DM, blood glucose control is more ideal, blood glucose fluctuations smaller.