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颈动脉窦压力感受器是调节循环血压水平的重要装置。本实验观察了慢性缺氧对该感受器功能的影响,并探讨了这种影响与慢性缺氧情况下血压改变的可能关系。实验用新西兰白兔24只。10只作为正常对照。其余置低压舱内模拟海拔5,000米高度减压缺氧10天(10只)与15天(4只)。然后,在常压下静注20％乌拉坦(5ml/kg)麻醉动物,游离并结扎其双侧颈总、内颈和外颈动脉,使颈动脉窦区形成一个盲袋,并通过颈总动脲插管与一带检
Carotid sinus baroreceptors are important devices that regulate circulating blood pressure levels. This experiment observed the impact of chronic hypoxia on the function of the sensor and explored the possible relationship between this effect and changes in blood pressure under chronic hypoxia. Twenty-four New Zealand white rabbits were used in experiment. 10 as a normal control. The rest of the low pressure cabin simulated altitude 5,000 meters altitude hypoxia 10 days (10) and 15 days (4). Then, 20% of urethane (5 ml / kg) was anesthetized at normal pressure, the bilateral common carotid, internal and external carotid arteries were dissociated and ligated, a blind bag was formed in the carotid sinus area, Urea catheterization and a belt inspection