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2型糖尿病是一种除心血管疾病、肿瘤外严重危害人类健康与生命的疾病。由于2型糖尿病的危害性和复杂性以及高发病率和高速度的发病率特点,给个人、家庭和社会带来了巨大压力和沉重的负担。对新诊断的2型糖尿病患者进行胰岛素泵(Subcutaneous insulin infusion,CSII)强化治疗是唤醒胰岛β细胞功能的有效手段,可减轻糖毒性、脂毒性及控制炎症,增加胰岛素敏感性,但无法遏制或延缓β细胞功能衰竭。从中医角度来看与胰岛素抵抗和β细胞功能密切相关的湿热证并没有解除。中医经典方剂葛根芩连汤(Gegen Qinlian Decoction,GQD)是治疗湿热证消渴的有效方剂,并可能在改善胰岛素抵抗,调节血脂等一定作用,对于新诊断的2型糖尿病患者,采用分阶段治疗暨在接受CSII早期强化治疗后服用以GQD为代表的清热祛湿之中药,可取得更好的疗效。
Type 2 diabetes is a disease that, in addition to cardiovascular diseases and tumors, seriously endangers human health and life. Due to the harmfulness and complexity of type 2 diabetes and the characteristics of high morbidity and high speed morbidity, enormous pressure and heavy burden are imposed on individuals, families and society. Subcutaneous insulin infusion (CSII) intensive treatment of patients with newly diagnosed type 2 diabetes is an effective means of arousing pancreatic β-cell function, reducing sugar toxicity, lipotoxicity, and inflammation, increasing insulin sensitivity but not deterring or Delay β-cell failure. From the perspective of traditional Chinese medicine and insulin resistance and β-cell function is closely related to damp-heat syndrome has not been lifted. Gegen Qinlian Decoction (GQD), a classic prescription of traditional Chinese medicine, is an effective prescription for the treatment of diabetes mellitus with damp-heat syndrome and may play a role in improving insulin resistance and regulating blood lipids. The newly diagnosed type 2 diabetes patients are treated with phased treatment Cum in the early intensive treatment of CSII taking GQD as the representative of the heat dampness of Chinese medicine, can achieve better efficacy.