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作者将子宫切除术患者随机分成预防给药组和安慰剂对照组,预防给药组投给三剂头孢唑啉,根据临床试验结果,分析了子宫切除术患者应用抗生素预防感染的效益。在住院期间伴有手术部位感染、泌尿道感染或发热的患者平均额外费用,经阴道子宫切除术者为1777美元,经腹部子宫切除术者为716美元。预防应用头孢唑啉后,使经阴道子宫切除术者住院期间感染发生率从52％下降到23％(预防率为56％),结果平均每个患者
The authors randomized the patients who underwent hysterectomy into prophylactic and placebo groups and prophylactic triamcinolone. The effectiveness of antibiotics in the prevention of infection in hysterectomy patients was analyzed based on clinical trials. Average additional costs for patients with surgical site infections, urinary tract infections, or fever during hospitalization were $ 1,777 for transvaginal hysterectomy and $ 716 for hysterectomies. After prevention of cefazolin application, the incidence of in-hospital infections during vaginal hysterectomy decreased from 52% to 23% (prevention rate 56%), with the result that on average each patient