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目的：测定肝硬变及原发性肝癌患者血浆MTL水平，并初步探讨其变化的意义。方法；肝硬变患者43例；原发性肝癌36例，其中伴肝硬变32例；慢性胃炎32例；消化性溃疡35例；正常对照组40例。血浆MTI。用放射免疫法测定。结果：血浆MTL。慢性胃炎［（336．55±68．12）ng／L］、消化性溃疡[（356．24±83．74）ng／L］与正常对照组［（327．65±71．37）ng／L]比较均差异不显著（P＞0．05）；肝硬化［（540．68±166．72）ng／L］，原发性肝癌［（501．56±156．44）ng／L]血浆MTL含量显著升高，与正常对照组比较差异非常显著（P＜0．01）。结论：测定血浆MTL对肝硬变和原发性肝癌的诊断具有一定的临床意义。
Objective: To determine the plasma MTL levels in patients with hepatic cirrhosis and primary liver cancer, and to explore the significance of the changes. Methods; 43 cases of cirrhosis patients; 36 cases of primary liver cancer, including 32 cases of cirrhosis; chronic gastritis in 32 cases; peptic ulcer in 35 cases; normal control group in 40 cases. Plasma MTI. Determined by radioimmunoassay. Results: Plasma MTL. Chronic gastritis [(336.55±68.12) ng/L], peptic ulcer [(356.24±83.74) ng/L] and normal control group [(327.65±71.37) ng/ L] The mean difference was not significant (P>0.05); Liver cirrhosis [(540.68±166.72) ng/L], primary liver cancer [(501.56±156.44) ng/L] The plasma MTL content increased significantly compared with the normal control group (P<0.01). Conclusion: The determination of plasma MTL has certain clinical significance in the diagnosis of cirrhosis and primary liver cancer.