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1974年4~9月外用1%克霉唑霜治疗了各种表皮癣菌病包括体癣、股癣、叠瓦癣、手癣、足癣、皮肤念珠菌病和花斑癣824例,取得了平均有效率94.4%和治愈率64.2%的结果,除9例(1%~+)发生接触性皮炎外,无其它不良反应。现已在本市推广应用。824例中,有550例真菌检查阳性,阳性率83.6%,其中红色癣菌占半数以上(62.9%),对克霉唑最敏感(MIC<1微克/毫升),其它相对较少。克霉唑系上海第二制药厂供应。体、股癣(有效率89.8%,痊愈率71.2%)和皮肤念珠菌病(有效率95.2%,痊愈率80.9%)外用1%克霉唑霜1天或擦药2~3次后,痒感即减轻,3天后皮损显著好转,1
From April to September 1974, a topical 1% clotrimazole cream was used to treat 824 cases of various dermatophytosis, including tinea corporis, jock itch, folds, ringworm, athlete’s foot, cutaneous candidiasis and pityriasis versicolor The average effective rate of 94.4% and the cure rate of 64.2% of the results, in addition to 9 cases (1% ~ +) of contact dermatitis, no other adverse reactions. Now in the city to promote the application. Of the 824 cases, 550 were positive for fungus, with a positive rate of 83.6%. Of these, Trichophyton rubrum accounted for more than half (62.9%), most sensitive to clotrimazole (MIC <1 μg / ml), and others were relatively rare. Clotrimazole is the second Shanghai Pharmaceutical Factory supply. Body, jock itch (effective rate 89.8%, cure rate 71.2%) and cutaneous candidiasis (effective rate 95.2%, cure rate 80.9%) topical 1% clotrimazole cream 1 day or rub the medicine 2 to 3 times, itchy Sense of relief, 3 days after the skin lesions significantly improved, 1