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目的 探讨骨肉瘤与转移性骨肿瘤介入治疗的靶动脉及化疗药物的选择。方法 对15例骨肉瘤和转移性骨肿瘤病人进行动脉灌注化疗,其中2例进行栓塞治疗并手术,对不同性质来源的肿瘤采用不同的化疗药物。结果 所有经介入治疗的病人疼痛症状均缓解或消失,并有不同程度的软组织块影缩小、肿瘤血管减少等表现,1例出现骨质增生修复。结论 在骨肉瘤与转移性骨肿瘤介入治疗中联合用药疗效优于单一用药。
Objective To investigate the choice of target artery and chemotherapy drugs for osteosarcoma and metastatic bone tumors. Methods Arterial infusion chemotherapy was performed on 15 patients with osteosarcoma and metastatic bone tumors. Two of them received embolization and surgery. Different chemotherapy drugs were used for tumors of different origins. Results The pain symptoms of all interventional patients were relieved or disappeared, and there were different degrees of soft tissue shadow shrinkage, tumor blood vessel reduction, etc., and one case had bone hyperplasia repair. Conclusion The combined use of drugs in interventional treatment of osteosarcoma and metastatic bone tumors is superior to single drug therapy.