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对41例肺心病急性加重期患者和20例正常人血浆纤溶酶(PL)活性测定,结果表明肺心病呼吸衰竭组与无呼吸衰竭组的PL活性与正常对照组相比均降低,有显著差异(P<0.001、P<0.01)。并证明肺心病消化道出血的主要原因是缺氧与高碳酸血症,与PL活性降低无关。同时对肺心病呼吸衰竭的9例患者进行了治疗前、后PL活性及血气分析对比,发现治疗后PL活性高于治疗前与血气分析的改善相一致(P<0.001)。可见PL活性测定对观察肺心病患者的疗效和判断预后有一定的实用价值。
41 cases of acute exacerbations of pulmonary heart disease and 20 cases of normal plasma plasminogen (PL) activity determination showed that pulmonary heart disease respiratory failure group and non-respiratory failure PL activity were lower than the normal control group, there was significant Difference (P <0.001, P <0.01). And to prove the main cause of pulmonary heart disease gastrointestinal bleeding is hypoxia and hypercapnia, PL activity has nothing to do with. At the same time, 9 patients with respiratory failure of pulmonary heart disease were compared before and after PL activity and blood gas analysis. The PL activity after treatment was higher than that before treatment and blood gas analysis was consistent (P <0.001). Visible PL activity determination of the observation of patients with pulmonary heart disease efficacy and prognosis have some practical value.