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目的探讨平顶山地区小儿呼吸道感染病原体感染情况。方法对640例小儿呼吸道感染患者的血清标本采用间接免疫荧光法(indirect flaorescent antibody,IFA)同时检测九项主要病原体的Ig M抗体,包括肺炎支原体(mycoplasma pneumonia,MP)、乙型流感病毒(influenza B virus,IFB)、呼吸道合胞病毒(respiratory syncytial virus,RSV)、腺病毒(adenovirus,ADV)、副流感病毒(parainfluenza virus,PIVS)、肺炎衣原体(chlamydia pneumonia,CP)、噬肺军团菌(legionella pneumophila,LP)血清1型、Q热立克次体(Q coxiella burneti,QC)、甲型流感病毒(influenza A virus,IFVA)。计数资料采用Fisher确切概率法,P<0.05为差异有统计学意义。结果 MP阳性率为12.66%(81例);IFB阳性为7.19%(46例);PIVS,阳性率2.19%(14例);ADV阳性率2.19%(14例);RSV阳性率1.25%(8例);CP阳性率0.16%(1例);其余病原体阳性率均为0.00%。不同年龄段的呼吸道感染的小儿感染9种非典型呼吸道病原体阳性率比较有差异有统计学意义(P<0.05)。结论 MP和IFB是平顶山地区小儿呼吸道感染感染的主要病原体,应予以重视,合理用药。
Objective To investigate the infection of pathogens in children with respiratory tract infection in Pingdingshan area. Methods Serum samples from 640 pediatric patients with respiratory tract infection were tested for indirect immunofluorescence (IFA) to detect IgM antibodies of nine major pathogens, including mycoplasma pneumonia (MP) and influenza B (influenza B) B virus, respiratory syncytial virus (RSV), adenovirus (ADV), parainfluenza virus (PIVS), chlamydia pneumonia (CP), Legionella pneumophila Legionella pneumophila (LP) serotype 1, Q coxiella burneti (QC), influenza A virus (IFVA). Counting data using Fisher exact test, P <0.05 for the difference was statistically significant. Results The positive rate of MP was 12.66% (81 cases), the positive rate of IFB was 7.19% (46 cases), the positive rate of PIVS was 2.19% (14 cases), the positive rate of ADV was 2.19% (14 cases) Cases); CP positive rate of 0.16% (1 case); the remaining positive rate of pathogens were 0.00%. There were significant differences in the positive rates of 9 kinds of atypical respiratory pathogens between children infected with respiratory tract infection of different ages (P <0.05). Conclusion MP and IFB are the main pathogens of infection of respiratory tract infection in children in Pingdingshan area, which should be paid attention to and used rationally.