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目的探讨心脑钠肽(BNP)与D-二聚体同心房颤动血栓栓塞并发症的关系；方法从我院2012年3月~2014年3月收治的心房颤动并发血栓栓塞患者中选取40例为观察组，另选同期未发生血栓栓塞心房颤动患者40例为对照组，对两组患者行超声心动图检查，同时采用化学发光免疫法及ELISA法对两组患者血清BNP、D-二聚体进行检测，观察两组患者超声心动图情况及血清BNP、D-二聚体含量；结果观察组血清BNP及D-二聚体含量同对照组比较，显著较高，差异存在统计学意义(<0.05)；结论心房颤动并发血栓栓塞患者血清BNP及D-二聚体含量较高，两者具有较紧密联系，对诊断与治疗具有重要指导价值。“,”Objective To investigate the heart and brain natriuretic peptide (BNP) and D-dimer between two concentric atrial fibril ation thromboembolism complication. Methods From 2012 March to 2014 March in our hospital were atrial fibril ation patients with thromboembolism in selected 40 cases for the observation group, select the same period without the occurrence of blood embolism in patients with atrial fibril ation 40 cases in the control group, two groups of patients underwent ultrasound examination of electrocardiogram, the simultaneous detection of two groups of patients with serum BNP, D-dimer by chemiluminescence immunoassay method and ELISA method, two groups were observed in patients with ECG and serum BNP, D-dimer content.Results The observation group of two BNP and D-dimers in compared with the control group, significantly higher, there were significant dif erences ( <0.05). Conclusion Complicated with thromboembolism in patients with BNP and two D-dimer content was higher in atrial fibril ation, the two have more closely, and have important directive value to the diagnosis and treatment of.