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苯乙腈在氢氧化钠、1-溴丁烷及相转移催化剂聚乙二醇作用下可顺利地发生α-丁基化反应,不同分子量的聚乙二醇具有不同的催化效力,溶剂、温度及催化剂用量对本反应均有重要影响.
Benzeneacetonitrile can a-butylate smoothly under the action of sodium hydroxide, 1-bromobutane and phase transfer catalyst polyethylene glycol. Different molecular weights of polyethylene glycol have different catalytic efficiency, solvent, temperature and The amount of catalyst has an important impact on the reaction.