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我院1991年1月至1992年9月,共收治伤寒病人151例,其中伤寒杆菌培养阳性52例,对伤寒菌株的耐药谱及R 质粒进行研究(观察组)。并与1987～1990年随机抽出50例伤寒杆菌培养阳性病人作对比(对照组),现总结如下。材料与方法一、临床资料52例中男29例,女23例,年龄最小8岁,最大60岁,平均30.9岁。对照组性别、年龄构成基本相似。对照组35例采用氯霉素加SMZ—TMP,或氨苄青霉素、庆大霉素、氧哌嗪青霉素等药治疗;15例为氟哌酸加丁胺卡那霉素。观察组选用氟嗪酸加丁胺卡那霉素治疗。
Our hospital from January 1991 to September 1992, a total of 151 cases of typhoid fever patients, 52 cases of typhoid fever positive culture, the resistance spectrum of typhoid strains and R plasmid (observation group). And with 1987 to 1990 randomly selected 50 cases of Salmonella typhi culture positive patients for comparison (control group), are summarized as follows. Materials and methods First, the clinical data 52 cases of 29 males and 23 females, the youngest 8 years old, maximum 60 years old, average 30.9 years. Control group gender, age composition is basically similar. The control group of 35 patients treated with chloramphenicol plus SMZ-TMP, or ampicillin, gentamicin, piperacillin penicillin and other drugs; 15 cases of norfloxacin plus amikacin. The observation group used fluorozine acid plus amikacin treatment.