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目前认为用自来水制备透析液析出的铝是透析脑病和抗维生素 D 软骨病的主要病因。作者报告15例透析治疗的尿毒症病人血液学和血清铝的变化,证明高铝透析液能引起可逆性非缺铁性小细胞低色素性贫血。15例慢性透析尿毒症病人,年龄21～58岁,在旧透析单位(A)治疗23±5个月,用未处理自来水制备透析液,含铝高(100～450μg/L)。后来病人转到新单位(B),用去离子水制备透析液,含铝低(<10μg/L),观察了12个月。每用透析3次,每次5小时,用再循环单道式透析机和铜酚膜蟠管型透析器。
At present, it is thought that the aluminum precipitated from tap water is the main cause of dialysis encephalopathy and anti-vitamin D cartilage disease. The authors report the hematology and serum aluminum changes in 15 patients with uremia treated with dialysis, demonstrating that high-aluminum dialysates can cause reversible non-iron-deficient micronucleus hypochromic anemia. Fifteen patients with chronic dialysis uremia, aged 21-58 years, were treated with the old dialysis unit (A) for 23 ± 5 months. Dialysate was prepared from untreated tap water and contained aluminum (100-450 μg / L). The patient was later transferred to a new unit (B), dialysate was prepared with deionized water, low in aluminum (<10 μg / L) and observed for 12 months. Each dialysis 3 times, 5 hours each time, with a single-channel dialysis recirculation and copper phenol Panpan dialyzer.