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目的:对血清生化指标变化情况与脂肪肝疾病患者体重指数和年龄之间的关系进行探讨。方法:选择在我院就诊的患有脂肪肝疾病的患者226例,和同期接受健康体检的年龄段健康人资料226例,分别定义为研究组和对照组。对两组研究对象血清谷丙转氨酶、谷草转氨酶、谷氨酰转肽酶、总胆固醇、甘油三酯、高密度胆固醇脂蛋白、低密度胆固醇脂蛋等血清生化指标水平进行测定,并对比结果,同时分析上述指标变化情况与该疾病患者体重和年龄之间的关系。结果:研究组研究对象血清谷丙转氨酶、谷草转氨酶、谷氨酰转肽酶、总胆固醇、甘油三酯、低密度胆固醇脂蛋等血清生化指标水平明显高于对照组,高密度胆固醇脂蛋白水平明显低于对照组;中青年患脂肪肝疾病的人数最多,其中超重和肥胖患者占70%以上。结论:脂肪肝疾病患者的血清生化指标会出现明显异常,且中青年肥胖或超重者属于该疾病的高发人群。
Objective: To explore the relationship between the changes of serum biochemical indexes and the body mass index and age of patients with fatty liver disease. Methods: A total of 226 patients with fatty liver disease and 226 healthy subjects of the same age undergoing physical examination were selected as our study group and control group respectively. Serum levels of alanine aminotransferase, aspartate aminotransferase, glutamyl transpeptidase, total cholesterol, triglyceride, high density cholesterol lipoprotein and low density cholesterol lipoprotein in two groups of subjects were measured, and compared the results, At the same time, we analyzed the relationship between the above indexes and the weight and age of the patients. Results: Serum levels of alanine aminotransferase, aspartate aminotransferase, glutamyl transpeptidase, total cholesterol, triglyceride and low-density cholesterol lipoprotein in the research group were significantly higher than those in the control group, high-density cholesterol lipoprotein Significantly lower than the control group; young people suffering from fatty liver disease, the largest number, of which overweight and obese patients accounted for more than 70%. Conclusion: The serum biochemical indexes of patients with fatty liver disease will be obviously abnormal, and young or middle-aged people who are overweight or obese belong to the high risk group of the disease.