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目的探讨高校教职工非酒精性脂肪性肝病(NAFLD)的患病情况以及同相关疾病的关系。方法收集某高校1 278例教职工的体检结果,采用χ2检验比较不同年龄、性别的NAFLD患病率,采用χ2检验比较NAFLD组和非NAFLD组脂代谢异常、高血压、高血糖、高尿酸的患病率。结果该高校教职工NAFLD检出率为35.52%。60岁以下男性NAFLD患病率高于女性(P<0.01),60岁及以后女性NAFLD患病率高于男性(P<0.01)。NAFLD组中脂代谢异常、高血压、高血糖、高尿酸患病率明显高于非NAFLD组。结论该高校教职工的NAFLD患病率较高,尤其是男性和60岁以上的女性。NAFLD的形成不仅仅和脂代谢障碍有密切关系,而且合并有高脂血症、高血压、高血糖、高尿酸等多种代谢紊乱的全身性疾病。防治NAFLD重在生活方式的根本改变,因此,应加强健康教育,改变不良生活方式。
Objective To investigate the prevalence of non-alcoholic fatty liver disease (NAFLD) in university faculty and its relationship with related diseases. Methods The physical examination results of 1,278 faculty members in a university were collected. The prevalence of NAFLD in different age and sex was compared by χ2 test. The χ2 test was used to compare the lipid metabolism, hypertension, hyperglycemia, hyperuricemia Prevalence. Results The detection rate of NAFLD was 35.52%. The prevalence of NAFLD in men under 60 years old was higher than that in women (P <0.01), and the prevalence of NAFLD in women 60 years old and later was higher than that in men (P <0.01). NAFLD group abnormal lipid metabolism, hypertension, hyperglycemia, high prevalence of uric acid was significantly higher than non-NAFLD group. Conclusions The prevalence of NAFLD among faculty members in this university is high, especially in males and females over the age of 60. The formation of NAFLD is not only closely related to dyslipidemia, but also has systemic diseases such as hyperlipidemia, hypertension, hyperglycemia, hyperuricemia and other metabolic disorders. Prevention and treatment of NAFLD emphasis on fundamental changes in lifestyle, therefore, health education should be strengthened to change the way of life.