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作者对患有或未患腰椎骨折的绝经后妇女的骨密度测量进行了研究分析,旨在比较L-DXA和mL-DXA对骨折诊断的敏感性。材料和方法:共240例绝经后妇女。根据各胸腰椎(胸4至腰4)倒位X线平片所见,并采用目视半定量法判断椎体的骨折或其程度,腰椎骨密度值分别选用L-DXA和mL-DXA所测数据。结果:骨折组的年龄高于非骨折组,而其BMD值则低于非骨折组。分析比较L-DXA和mL—DXA的结果表明其下降百分数和Z分数相似,ROC曲线下面积也无显著性差异,logistic回归分析中,两者年龄调整后的优势比无显著性差异。进一步将正常与轻度骨折组比较,两者的ROC面积仍无显著性差异。结论:在区分正常与骨折以及正常与轻度骨折时,mL-DXA并不优于L-DXA。因轻度骨折的L-DXA和mL-DXA所测骨密度值均低于非骨折组,故应视其为骨折。
The authors studied bone mineral density measurements in postmenopausal women with or without lumbar fractures and compared the sensitivity of L-DXA and mL-DXA to fracture diagnosis. Materials and Methods: A total of 240 postmenopausal women. According to each thoracolumbar spine (chest 4 to lumbar 4) inverted X-ray plain film and visual semi-quantitative method to determine the extent of vertebral fractures, lumbar BMD were selected L-DXA and mL-DXA Test data. Results: The age of fracture group was higher than that of non-fracture group, while the BMD of fracture group was lower than non-fracture group. Analysis of the results of L-DXA and mL-DXA showed that the percent decrease and the Z-score were similar, and there was no significant difference in area under the ROC curve. Logistic regression analysis showed that there was no significant difference in age-adjusted superiority between the two groups. Further analysis of normal and mild fracture group, the two areas of ROC still no significant difference. CONCLUSION: mL-DXA is not superior to L-DXA in distinguishing between normal and fractures and normal and mild fractures. The bone mineral density measured by L-DXA and mL-DXA in mild fractures were lower than those in non-fractured group, so they should be regarded as fractures.