应用抗肿瘤抗生素治疗小儿肾胚细胞瘤

• 作 者: 于守汛
• 出 处: 国外药学(抗生素分册)
• 发表日期: 1985年04期
• 关键词: 肾胚细胞瘤 抗肿瘤抗生素 膜破裂 术前化疗 外科手术 放线菌素 长春新碱 化学疗法 超声描记 肾肿瘤切除术

目前公认,外科手术、化疗和放疗的综合疗法是治疗小儿肾胚细胞瘤的有效措施.此种疗法可使患者的生存期延长,甚至对于贻误早期治疗的病例,也可使60～80%患者的生存期延长二年以上.术前化疗具有使肿瘤缩小而易于切除、防止术中被膜破裂、确定化疗药品抗肿瘤的敏感性以及早期抑制转移瘤生长的作用.后

It is now recognized that the combination of surgery, chemotherapy and radiotherapy is an effective treatment for children with renal blastoma. This type of therapy can extend the survival of patients, even for early treatment of cases, but also can make 60 to 80% of patients The survival period is prolonged for more than two years. Preoperative chemotherapy has the effect of reducing the size of the tumor and facilitating its resection, preventing the rupture of the capsular in the operation, determining the antitumor susceptibility of chemotherapy drugs, and early suppression of the growth of metastatic tumors.