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目的探讨阿魏酸钠、低分子肝素联用治疗不稳定型心绞痛的临床疗效。方法72例不稳定型心绞痛病人,分为治疗组和对照组各36例。所有病人根据病情给予常规药物治疗。对照组在常规治疗的基础上加用低分子肝素治疗;治疗组在常规治疗的基础上加用阿魏酸钠及低分子肝素联合治疗。两组疗程均为10~14 d。结果治疗组在缓解症状、心电图改变及硝酸甘油消耗量方面均明显优于对照组(P<0.05)。结论不稳定型心绞痛病人在常规治疗的基础上联合使用阿魏酸钠和低分子肝素,疗效确切,副作用小。阿魏酸钠可作为治疗不稳定型心绞痛的一种有效药物。
Objective To investigate the clinical effect of sodium ferulate and low molecular weight heparin in the treatment of unstable angina pectoris. Methods 72 cases of unstable angina patients, divided into treatment group and control group of 36 cases. All patients according to the condition given conventional drug treatment. The control group was treated with LMWH on the basis of routine treatment. The treatment group was treated with sodium ferulate and LMWH on the basis of routine treatment. The two courses of treatment were 10 ~ 14 d. Results The treatment group was significantly better than the control group in relieving symptoms, ECG changes and consumption of nitroglycerin (P <0.05). Conclusion Unstable angina patients combined with sodium ferulate and LMWH on the basis of routine treatment have definite effect and small side effects. Sodium ferulate can be used as an effective drug in the treatment of unstable angina pectoris.