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目的:观测急性脑梗死患者血清中IL-4和IL-6水平的变化,探讨其临床意义。方法:采用ELISA法测定28例急性脑梗死病人和36例正常人血清中IL-4和IL-6水细胞因子含量。结果:急性脑梗死病人血清中IL-4和IL-6水平分别为45.0±12.6和48.4±18.2,较正常对照组明显增高(P(0.01)。结论:急性脑梗死病人机体免疫功能紊乱,血清中IL-4和IL-6水平的变化可能与疾病的发生、发展有关系。
Objective: To observe the changes of serum levels of IL-4 and IL-6 in patients with acute cerebral infarction and to explore its clinical significance. Methods: Serum levels of IL-4 and IL-6 in 28 patients with acute cerebral infarction and 36 healthy controls were measured by ELISA. Results: Serum levels of IL-4 and IL-6 in acute cerebral infarction patients were 45.0 ± 12.6 and 48.4 ± 18.2, respectively, which were significantly higher than those in normal controls (P <0.01) .Conclusion: The immune function of patients with acute cerebral infarction is abnormal, Changes in IL-4 and IL-6 levels may be related to the occurrence and development of the disease.