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Object: To obtain epidemiological data on Traditional Chinese Medicine (TCM) therapeutic status of acute myocardial infarction (AMI) and to determine TCM characteristics and advantages to improve the level of TCM prevention and treatment of AMI.Methods: Clinical epidemiology methods were used to register and survey the TCM therapeutic status of hospitalized AMI patients.In 2001,the Chinese Association of Integrative Medicine surveyed the therapeutic status of 3308 AMI patients hospitalized in 30 hospitals in Beijing and Shanghai from 2000-2001.The Beijing Collaborative Study Group on Therapeutic Status of Acute Myocardial Infarction (the Study Group) then conducted a 10-year-long register survey on hospitalized AMI patients in Third-grade A-Level TCM hospitals in Beijing.After 2002,the Study Group further surveyed the treatment conditions of AMI-hospitalized patients in 10 Second-grade A-Level TCM hospitals.The therapeutic status in 8 Third-grade A-Level Westem medicine hospitals was surveyed in 2001 and 2005 as a control.In 2008,in cooperation with the China Association of Chinese Medicine,the Study Group further performed a survey at 26 Third-grade A-Level TCM hospitals nation-wide.Approximately 5000cases were investigated to obtain authoritative data on the therapeutic status of AMI patients in TCM hospitals in China.Results: We found that Chinese herbal intravenous preparations may be beneficial in reducing the mortality of AMI.Major complications of AMI,such as heart failure and arrhythmia,were significantly less during the 10-year survey period.The mortality of hospitalized AMI patients showed a decline.TCM treatment was helpful for AMI patients in improving their quality of life.Ten-year dynamic monitoring showed that the ability to perform reperfusion and to use drugs appropriately,as well as an effort to carry out the Clinical Guidelines has made great progress in TCM hospitals.However,TCM hospitals still have some problems in treating AMI,including a lack of standardized TCM syndrome diagnosis,the need for syndrome differentiation and treatment standardization,and clinical skills in reperfusion and standardized drug treatment still need to be further improved.Compared with AMI patients in West medicine hospitals during the same period,those in TCM hospitals had the following characteristics: they were admitted to hospital later; they were older when they had a heart attack; there were more females,they had more problems in their medical history,and they had more concomitant illnesses and complications.Therefore,the demographic baseline data were significantly different between AMI patients in TCM hospitals and those in West medicine hospitals.This indicated that patients in TCM hospitals were more critical than those in West medicine hospitals.Conclusions: TCM has special advantages in treating AMI.TCM hospitals are making continuous progress in standardized treatment of AMI,but further improvement is still required.AMI patients in TCM hospitals have some special characteristics,and their condition may be more critical.Further clinical research on TCM treatment of AMI is required.