论文部分内容阅读
采用ELISA法测定20例支气管哮喘患儿(观察组,其中急性发作期7例,缓解期13例)血清白细胞介素—13和IgE的水平,并与20例体检正常的儿童(对照组)进行对照。对哮喘发作期IL-13与IgE的水平进行相关分析。结果IL-l3和IgE水平显著高于缓解期和对照组(P均<0,05)。IL-13与lgE呈正相关,分析IL-13参与支气管哮喘发病的整个过程。检测血清IL-13及IgE水平可反映支气管哮喘的炎症状态及评价治疗效果。
Serum levels of IL-13 and IgE were measured in 20 children with bronchial asthma (observation group, 7 acute exacerbation and 13 remission) by ELISA, and were compared with 20 normal children (control group) Control. The levels of IL-13 and IgE during the asthma attack were analyzed. Results The levels of IL-13 and IgE were significantly higher than those in remission and control group (all P <0 05). IL-13 and lgE was positively correlated, the IL-13 involved in the pathogenesis of bronchial asthma in the whole process. Detection of serum IL-13 and IgE levels can reflect the inflammatory state of bronchial asthma and evaluate the therapeutic effect.