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目的评价舌下含服硝酸甘油倾斜试验 (GTTT)的安全性和对血管迷走性晕厥 (VVS)的诊断价值。方法 6 7例血管迷走性晕厥患者及 2 0例无晕厥史的健康人行基础倾斜试验 (BTTT) ,BTTT阴性者连续 2天随机作异丙肾上腺素倾斜试验 (ITTT)和 GTTT。结果晕厥组 BTTT阳性 2 0例 ,阴性反应的 47例中 GTTT阳性 30例 ,ITTT阳性 31例 ;对照组 BTTT、GTTT和 ITTT分别有 1、1和 2例阳性 ,ITTT和 GTTT的敏感性和特异性分别为 6 8.9%对 6 3.8%和 89.4%对 94.7%。结论 GTTT是诊断 VVS安全而有效的方法 ,其敏感性和特异性与 ITTT相似 ,患者有较好的耐受性
Objective To evaluate the safety of sublingual nitroglycerin tilt test (GTTT) and the diagnostic value of vasovagal syncope (VVS). Methods Sixty-seven patients with vasovagal syncope and 20 healthy subjects with no history of syncope were included in this study. Patients with BTTT were randomized to receive ITTT and ITTT for 2 consecutive days. Results There were 20 BTTT positive cases in the syncope group, 30 GTTT positive cases and 31 ITTT positive cases in 47 cases of negative reaction. The BTTT, GTTT and ITTT in the control group were 1, 1 and 2 cases positive respectively, the sensitivity and specificity of ITTT and GTTT Sexual differences were 6 8.9% vs 6 3.8% and 89.4% vs 94.7% respectively. Conclusion GTTT is a safe and effective method for the diagnosis of VVS. Its sensitivity and specificity are similar to those of ITTT, and patients have better tolerability