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顺铂的耳毒性和肾毒性作用已被许多动物实验和临床应用所证实。耳毒性主要作用部位在耳蜗外毛细胞。但是在应用顺铂后铂在外毛细胞内的定位尚不明了。为此用X线微量分析和离子显微观察钻在豚鼠耳蜗和肾脏的存在部位。方法是给杂色豚鼠肌肉注射1·sins儿g顺钻（CDDP）第一组9只?
The ototoxic and nephrotoxic effects of cisplatin have been demonstrated in many animal experiments and clinical applications. The main role of ototoxicity in the cochlear outer hair cells. However, the localization of platinum in the outer hair cells after cisplatin application is unknown. For this purpose with X-ray microanalysis and ion microscopic observation of guinea pig cochlear and kidney existing sites. The method is to intramuscular injection of variegated guinea pig 1 · sins children g along the first drill (CDDP) 9?